Never give up on what you really want to do. The person with big dreams is more powerful than one with all the facts.
Those who are willing to give up are usually going to be those of the majority, while those who are willing to stand-alone are usually those who are more handsomely rewarded. This life is full of many roads, many different opportunities, and many different limitations, because frankly we are all different in a multitude of ways.
One thing that is common between those who are successful in life, though they often times walk very different paths to achieve their successes is the fact that at certain points in their lives when they could have easily given up, they refused to. The concept of refusing to give up, may be a somewhat cliche or outdated one, but it is one that almost never fails. The attitudes that you consistently display throughout your life will help to write your legacy, refuse to be remembered as a quitter.